Abstract
Summary
The susceptibility ranges of a fibroblast-like and 6 epithelial-like human cell strains to 16 ECHO virus types have been described. All of these ECHO viruses except type 10 multiplied in the fibroblast-like cell strain (Detroit-196 Fb-L). In contrast, an epithelial-like strain (Detroit-196 Ep-L) evolving from the Fb-L strain, as well as 5 additional Ep-L cell strains, either were refractory or had narrow susceptibility ranges. The significance of differences in morphology with respect to virus susceptibility was discussed.
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