Abstract
Summary
The mouse tail reaction to morphine is not suppressed by mephenesin or zoxazolamine at minimal paralyzing dose levels. On the other hand, it is markedly suppressed by phenobarbital, chloral hydrate, meprobamate, and Dilantin at sedative dosages. The lack of a suppressive influence of an agent on the morphine-induced tail response in mice at paralyzing doses is suggested as a confirmatory test for mephenesin-like property.
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