Abstract
Summary
The effects of urinary volume, diet, and exercise on long term endogenous creatinine clearance were studied on normal individuals using the ortho-nitrobenzaldehyde method for creatinine. Urinary volume variations had no effect on creatinine clearance; protein ingestion and exercise seemed to increase slightly the clearance values. One hour clearances were similar to 24 hour clearances. Long term creatinine clearances of 39 normal individuals of varying age groups were determined and were found to be similar to reported inulin clearance values of these same age groups.
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