Abstract
Summary
An hemagglutination technic for the titration of antibodies to polioviruses has been described. The HA titers showed approximately a 75% correlation with neutralizing antibody. The virus-sensitized cells did not remain agglutinable for more than 2 days at 5°C, but have proven stable for at least 6 weeks when kept frozen. An antigenic cross among viral types of 12% was observed. Purified virus lessened the nonspecific HA, but not the percentage of cross reactions.
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