Abstract
Summary
1) The incidence of naturally occurring skin sensitization to a poison ivy allergen, PDC, and of experimentally induced skin sensitization to 2 chemical sensitizers, DNCB and NDMA, was determined in 23 patients with sarcoidosis and 135 control subjects. 2) The incidence of sensitization to the strongest sensitizer, PDC, was the same in the control group and in the patients with sarcoidosis. 3) With the less effective sensitizers, DNCB and NDMA, a significantly decreased frequency of sensitization was observed in the patients with sarcoidosis. 4) This finding with the latter compounds is consonant with the decreased incidence of delayed type hypersensitivity reactions observed by others using antigens injected intradermally.
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