Abstract
Summary
Kidney glutaminase and carbonic anhydrase activities were determined in intact and adrenalectomized rats maintained on normal and potassium-deficient diets, with and without simultaneous administration of DCA. The changes of enzyme activity could not be related to plasma or muscle electrolytes. The activities of the 2 enzymes were found unaltered in adrenalectomized rats. Experimental conditions resulting in increased glutaminase activity in adrenalectomized rats had the same effect to a greater degree in intact rats. Kidney carbonic anhydrase activity failed to increase in adrenalectomized rats under circumstances which in intact rats led to increased activity.
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