Abstract
Summary
The total volume of adrenocortical tissue regenerating in intramuscular autotransplants in rats during the first 2 weeks after operation is proportional to number of transplants growing. Thereafter, the total volume is about the same irrespective of the number of implants made or transplants regenerating, so the volumes per transplant are inversely proportional to the number of grafts. Average volume of regenerating tissue and cell depth increases with increasing age of transplant. At 90 days after operation the cell depth is like that of intact adrenal glands but the volume is less. Apparently transplants cannot deliver the amount of cortical secretion necessary to establish a pituitary-adrenal equilibrium until after 2 weeks of growth.
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