Abstract
Summary and Conclusions
Two new alkaloids from Rauwolfia canescens, pseudoreserpine and raunescine have been studied for pharmacologic activity in mice and dogs. Both pseudoreserpine and raunescine have reserpine-like activity, but are less potent than reserpine. The reduction in potency has been attributed to the substitution of the methoxyl group on C-17 in ring E by a hydroxyl group.
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