Abstract
Conclusions
Relaxin causes an increased concentration of water in the uterine tissue of the immature rat. Maximum hydration was obtained at 6 hours following administration of the hormone. The minimum effective dose of relaxin is 1 G.P.U. and the maximum response occurs following 10 G.P.U. relaxin. Contrary to the effect seen following estradiol administration, no secondary rise in uterine water content and no increase in dry weight is observed. Pretreatment with estrogen is not necessary for this action of relaxin on the water content of the uterine tissue.
Get full access to this article
View all access options for this article.