Abstract
Summary
1) The endogenous dehydrogenase enzyme activity, as measured by the tetrazolium technic, was determined in kidney, adrenal, thyroid, pituitary and heart tissue from untreated and reserpine treated hypertensive animals. Experimental renal hypertension was produced in rats by 3 different methods. 2) A reduction in endogenous dehydrogenase enzyme activity of kidney tissue was observed in hypertensive animals while the activity of cardiac muscle was increased. Treatment with reserpine resulted in a depression of the endogenous dehydrogenase enzyme activity in cardiac tissue of both hypertensive and normal animals.
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