Abstract
Summary
1. Young adult female CF No. 1 mice were irradiated with single whole-body exposures of fission neutrons with dose range sufficient to kill 20 to 90% in 30 days. Four spleens from 2-week-old mice were implanted into body cavities of half this group; the remaining mice served as sham-operated controls. 2. Spleens gave no obvious protection to these neutron-irradiated mice: There was no significant difference in either body weight loss or in 30-day mortality between spleen-implanted and sham-operated groups. 3. Implanted spleens provided some protection to similar mice exposed to single doses of Co60 γ-rays in the 30-day lethal range. 4. Failure of implanted spleens to protect neutron-irradiated mice may be correlated with early (4-10 day) mode of mortality following single doses of fission neutrons. 5. It seems probable that radiation with fast neutrons of different energies may give different results after treatment with blood-forming cells.
Get full access to this article
View all access options for this article.