Abstract
Summary
Normal rats placed in a low oxygen atmosphere did not elaborate in their plasma a factor capable of stimulating increased incorporation of Fe50 into red cells of normal or hypophysectomized recipients. However, when their liver was acutely damaged with carbon tetrachloride and they were then placed in low oxygen atmosphere, significant amounts of such a factor appeared in their plasma. This is interpreted as further evidence that the liver, under ordinary circumstances, has a significant part in the mechanisms that control red cell production.
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