Abstract
Summary
The normal trained dog, in fasting conditions, injected by vein with the sodium salt of carbutamide shows a definite decrease of blood sugar, but not significant changes in serum inorganic phosphate. Insulin and glucose produce a definite lowering of serum inorganic phosphate. It seems then, that carbutamide may not lead to a discharge of insulin by the pancreas. However, since the effect of carbutamide on blood sugar is gradual, it may be that its possible action on serum phosphate is masked by other mechanisms.
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