Abstract
Summary
Plasma, brain, and muscle electrolytes were determined in mice given DCA and aldosterone. DCA increased the concentration ratio of K (Kc/Ke) without affecting the ratio of Na (Nae/Nac) in brain; it increased the concentration ratio of K moderately in muscle and decreased the concentration ratio of Na. Aldosterone increased concentration ratios of Na and K in both brain and muscle. An explanation of this difference in the effect of the two steroids on skeletal muscle electrolyte is proposed.
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