Abstract
Summary
Glomerular filtration rate and renal plasma flow were determined by inulin and para-amino hippuric acid clearance tests in 19 normal subjects, in 14 cholera patients and in 6 patients suffering from acute gastroenteritis. In patients suffering from cholera and acute gastroenteritis, glomerular filtration rate and renal plasma flow were greatly diminished to the same degree, when these patients had apparently normal urination after transfusion of saline. The diminished clearance values might be due to renal anoxia causing temporary diminution in blood flow through the cortex of the kidney and not due to any specific toxins of the disease.
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