Abstract
Conclusion
Homografts of the rat ovary do not depend on vascularization to maintain the production of estrogenic substances up to 60 days. Semipermeable millipore filter membranes were used to form a chamber in which to embed ovarian transplants in previously castrated recipients. These chambers excluded leucocytes and prohibit vascularization, yet permitted passage of gonadotropic hormones. Vaginal smears and uterine weights demonstrated the production of estrogens from these grafts two months later. The functional survival of similar preparations in the monkey is now under investigation.
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