Effect of Carbon Tetrachloride Injury on Plasma and Liver Vitamin B 12 Levels

Abstract

Summary

(1) Administration of carbon tetrachloride increased the serum level of vit. B₁₂ of rats fed a casein diet. No similar increase was observed in rats previously offered a low vit. B₁₂ diet. (2) Administration of carbon tetrachloride likewise increased the urinary excretion of parenterally administered vit. B₁₂ or of absorbed vit. B₁₂ following oral administration. (3) Physiological significances of these findings are discussed.