Abstract
Summary
Marrow weights and the numbers of cells per mm3 in femoral marrow of erythrocytes, total leukocytes, immature and mature n. granulocytes were obtained in uninjured rats, bled rats, and rats given thermal injuries of 20% and 50% body surface. Significantly lower numbers of erythrocytes, total leukocytes and n. granulocytes were found in the thermally injured rats during first two weeks following injury compared to the numbers of these cells occurring at similar intervals in the uninjured controls and bled animals. The numbers of these cells following thermal injury were found to be inversely related to the percentage of body surface injured. These data support the conclusion that a suppressed medullary hematopoiesis occurs after thermal injury and is partially responsible for the circulatory anemia found in thermally injured animals.
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