Abstract
Summary
1. Broken-cell preparations of liver and of kidney from rats with constitutional nonhemolytic hyperbilirubinemia failed to synthesize bilirubin or o-aminophenol glucuronides. 2. Inhibition of β-glucuronidase with potassium saccharate failed to influence conjugation of bilirubin in these animals. 3. The evidence presented suggests that in constitutional nonhemolytic hyperbilirubinemia in rats, glucuronyl transferase activity is absent or inhibited.
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