Abstract
Summary
Control animals receiving inositol injections showed no deviation from the normal vascular pattern or reactions. However, the concentration of inositol administered (1 mg/100 g of body weight) markedly increased the tendency to hemorrhage. When inositol was injected into animals prior to induction of cold injury the initial responses of frostbite controls occurred without deviation. However, the constriction phase was ameliorated, thrombi formation was inhibited, and complete stasis was eliminated.
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