Abstract
Summary
Evidence is presented that while whole cell preparations of antibiotic resistant staphylococci did not oxidize pyruvate, lysed cell preparations did. Magnesium ions and Mg++ plus cocarboxylase, but not cocarboxylase alone, stimulated pyruvate oxidation by lysed cells, but had no effect on the activity of whole cells. Activity of isolated cell free extracts, cell surface components, and chelating ability of tetracycline are being studied.
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