Alteration of Plasma Electrophoretic Patterns and Anaphylactic Reactions in Protein Depleted Dogs. ∗

Abstract

Summary

1) Dogs were depleted of body proteins by forced hemoglobin production superimposed on a low protein diet. Electrophoretic patterns indicated markedly decreased albumin values and A/G ratios in spite of relatively little change in total plasma proteins. In all instances there were marked increases in total α, β and γ globulins. 2) Anaphylactic reactions following immunization to horse serum were diminished or absent in the depleted animals as contrasted to controls.