Abstract
Summary
Ten patients with hypercalcemia and hypercalcuria and 1 patient with normocalcemia and hypercalcuria were treated with 6-diazo-5-oxo-L-norleucine alone or in combination with 6-mercaptopurine. Full correction of hypercalcemia with treatment occurred in 8 of 13 instances in these patients. Correction of hypercalcuria was observed in 9 of 14 instances. Various possible mechanisms underlying these observed effects are considered.
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