Blood Levels of 17-Hydroxycorticosteroids in Hyperthermic Dogs. ∗

Abstract

Summary

Twenty-four dogs were subjected to an ambient temperature of sufficient magnitude to elevate rectal temperatures to 42.5†C for one hour. These animals were studied with regard to plasma 17-hydroxycorticosteroid concentration and plasma and erythrocyte electrolyte levels. Significant changes were observed in all measured variables with the exception of plasma Na concentration, which was not altered from the control value. The physiological implications of these data are discussed.