Abstract
Summary
The benzyl analog of bufotenin, BAB. or 1-benzyl-2,5-dimethylbufotenin (1-benzyl-2-methyl-5-methoxy-N, N-dimethyltryptamine hydrochloride) has been found to be a highly active antagonist of serotonin. Not only was it effective on isolated tissues, but. unlike many others, was highly active as an antagonist to the pressor effects of serotonin in dogs, even when given by the oral route. Some differences in action from the corresponding primary amine (benzyl analog of serotonin) were found.
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