Abstract
Summary
1. Oxidation of acetate to CO2 by the eviscerated-nephrectomized rabbit is unaffected by malonate. 2. Studies on the fate of carbon-14 labeled malonate indicate that the intracellular transfer rate of malonate is low. 3. Conversion of radioactive malonate to CO2. has been demonstrated in the eviscerated-nephrectomized rabbit. 4. The slow rate of cell entry and subsequent oxidation of malonate is offered as a possible explanation for the non-inhibitory effect of malonate on acetate oxidation.
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