Abstract
Summary
Measles virus has been adapted to a cancer cell strain derived from a human epithelioma. The Hep-2 cell strain provides a particularly useful system for the study of measles because of its growth characteristics in media free of human serum, its freedom from latent cytopathogenic agents, and the high yields of virus that may be rapidly obtained. After adaptation to Hep-2 the virus was still capable of infecting monkeys but caused little or no illness.
The authors wish to express their gratitude to J. S. Huang for his contributions in the first phase of this work and to Stephen Greenwald and Sigrid Angerer for their technical assistance.
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