Abstract
Summary
Of the 16 snake venoms studied, 11 actively lysed human blood clots. However, only one of these, C. basiliscus, was devoid of thrombic, hemolytic, and hemaggluti-nating properties. This venom was fibrino-genolytic as well as fibrinolytic. The possible therapeutic use of certain venoms as dissolving agents for intravascular clots presents a theoretical advantage over most other fibrinolytic agents in that their fibrinolytic activity is not readily inhibited by human serum. Fractionation of a pure fibrinolytic principle may be possible.
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