Abstract
Conclusion
1. Patients were made aci-dotic with intravenous ammonium chloride during a period when they were anemic and again during a period when the red blood count and hemoglobin values were normal. 2. No significant change in range of blood pH, bicarbonate, urinary pH or titratable acidity was demonstrated during and following infused ammonium chloride during the period of anemia as compared with the period of normal red blood count and hemoglobin levels. 3. No difference in response to infusion of sodium bicarbonate during the state of compensated metabolic acidosis was noted when the patients were anemic as compared with a normal red blood count and hemoglobin level. 4. Correction of a severe anemia is not important in overcoming ammonium chloride-induced metabolic acidosis or in the correction of the ammonium chloride-induced metabolic acidosis with sodium bicarbonate.
The authors wish to thank Miss Dorothy Zoeller and Miss Evelyn Warteberg, medical technologists, Milwaukee County General Hospital, for their assistance in performing some of the determinations in this study.
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