Abstract
Summary
(1) The egg white sensitized or normal mouse uterus is 1,000 times more sensitive to serotonin than it is to histamine. (2) This sensitivity is completely abolished in the presence of two known serotonin antagonists, LSD and reserpine. (3) LSD and reserpine, which as far as is known inhibit only serotonin, always and completely prevented the anaphylactic contraction on strips of demon-strably sensitized uterus in the ten trials with each drug.
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