Abstract
Summary
Rabbits and roosters injected with whole human semen, seminal plasma and washed spermatozoa produced antisera which showed a high degree of specificity for seminal antigens as compared with human serum and organ extracts. However, a distinction between seminal plasma and spermatozoa could not be obtained with immunological technics. Evidence which would make it seem likely that the dominant antigenic material is derived from the fluid constituents of the semen rather than from the spermatozoa is presented. Human spermagglutinating sera do not give complement fixation tests with seminal plasma or spermatozoa, but they produce a zone of precipitation with seminal plasma as antigen in the agar diffusion test.
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