Effect of Varying Dosages of Potassium Iodide in Experimental Atherosclerosis

Abstract

Summary

1. Groups of rabbits were fed a 2% cholesterol diet augmented with 0.001%, 0.01%, 0.1% and 1% potassium iodide, 0.1% diiodotyrosine, and one group received 0.15 mg of thyroxine weekly by intraperitoneal injection. 2. Serum cholesterol and lipoprotein levels of all animals were elevated, but atheromata were significantly reduced in those on diet containing 1% KI. The S_f 0-12 lipoprotein levels were also higher in animals of this group than in controls, but on the whole levels of liver cholesterol were lowest.