Abstract
Summary
Although thyroxine and ethanol possess diuretic activity when administered alone, the administration of 8.5% ethanol to rats pretreated with 20 μg of thyroxine per day for 7 days abolishes the diuretic action of the thyroxine. The ethanol block is not caused by a decrease in the rate of absorption of fluid from the intestine. The mechanism by which ethanol blocks the diuretic action of thyroxine is not apparent from the available data.
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