Abstract
Summary
1. Inhibitory properties of 3 chlorpromazine analogues show that oxidation at the sulfur atom, abolishes inhibition of ATP-ase and cytochrome oxidase systems by chlorpromazine. 2. Removal of chlorine atom from the ring viz: promazine, and alteration of the N-substituted sidechain viz: promethazine, result only in a small diminution of the inhibitory properties. 3. Inhibitory findings are correlated with known pharmacological effects of the drugs.
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