Abstract
Summary
1. Marked changes in the activities of 9 enzyme systems were observed at the height of poliomyelitis infection in vitro. 2. The decrease of alkaline phosphatase, pentanucleotidase, simple nucleotidase, “acid”RNA-se and DNA-se is so marked, that this may serve as a quantitative measure of cytopathogenic effect of the poliomyelitis virus. 3. The bearing of these findings on cellular physiology and pathology is discussed, as a working hypothesis.
Get full access to this article
View all access options for this article.