Sedimentation Behavior of Desoxypentose Nucleic Acids from Normal and Pathologic Human Spleens

Abstract

Summary

1. Sedimentation curves of DNA from spleens of normal individuals and patients with diseases causing a leukocyte infiltration in the spleen were obtained by-means of the ultracentrifuge. 2. DNA was dissolved in cacodylate buffer (pH 7; u 0.3) at concentrations range 1-20 mg % of P DNA. No differences in sedimentation curves of DNA from normal and infiltrated spleens were noted.