Abstract
Summary
1. The work of Hall and Bieri on aggravation of choline deficiency by growth hormone has been confirmed. 2. Under suitable borderline conditions, growth hormone precipitates haemorrhagic lesions of the kidney in choline-deficient animals. With the advent of kidney lesions, cardiovascular changes appear. 3. These findings provide further evidence that the aetiology of cardiovascular lesions in choline deficiency is closely associated with kidney damage, but a causal relationship of one lesion to the other can not be established by experiments of this type. 4. Testosterone has effects similar to those of growth hormone in choline deficiency. 5. The mechanism of this aggravation of choline deficiency has been briefly discussed.
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