Abstract
Summary
Acute scurvy was produced in guinea pigs by paired feeding technic. Urinary excretion of injected PABA in the acetylated form was estimated in scorbutic and paired fed normal guinea pigs. Scorbutic animals excreted decreased amount of acetylated PABA. Co A activity of liver, kidney and brain of scorbutic and paired fed control guinea pigs was determined. Co A activity which was present in the tissues of normal guinea pigs did not change in scurvy. Total body cholesterol of scorbutic guinea pigs increased significantly. The implications of the results obtained have been discussed.
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