Abstract
Summary
A method is described whereby thromboplastic material is extracted from normal male human urine by adsorption on BaSO4 and subsequent elution. The thromboplastic material is comparatively resistant to heat; its activity is enhanced by incubation with serum and prothrombin-free plasma. As little as 6 μg/cc of the thromboplastic material per cc of hemophilic plasma was found to restore the clotting properties of this plasma to normal.
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