Abstract
Summary and Conclusions
In these experiments cortisone had no antisynthetic effect; its effect on protein synthetic reactions was to increase synthesis in the diaphragm. Since liver is spared and diaphragm is not spared against the wasting effects of cortisone, the chief effect of cortisone according to our observations must be its influence on catabolic reactions. Thus the organ-specific effects of cortisone can be explained on the basic of increased catabolism in diaphragm but not in liver.
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