Abstract
Conclusions
Previous observations that xanthine oxidase increases in mouse lung concomitant with influenza virus infection have been confirmed and extended. Comparable increases in xanthine oxidase also occur in murine pneumonitis produced by Nigg pneumonitis virus and by NDV. Comparative studies with other types of infection and injury indicate that infection with K. pneumoniae and the intrapleural injection of turpentine also result in significant increases in xanthine oxidase activity in mouse lung thus suggesting that an increase in the level of enzyme is closely associated with injury and death to lung tissue.
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