Abstract
Summary
Pre-medication with 5 mg/kg of zymosan intravenously or intraperitoneally did not significantly increase survival in irradiated mice. With intravenous injections of 125 mg/kg on pre-irradiation days 14 and 3, a significant reduction in the ST50 day was observed. Similar results were obtained with both doses when injections were given after irradiation. The beneficial effects of zymosan in the treatment of radiation injury in mice reported by Ross and Pillemer could not be confirmed.
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