Abstract
Summary
1. The KB and HeLa strains of human epidermoid carcinoma have been established in the cheek pouches of golden hamsters by means of quantitated suspensions prepared from tissue cultures in a medium providing the specific amino acid and vitamin requirements of these cell lines. 2. Strain KB, isolated directly from a biopsy specimen in these media, has been grown in LAFi mice bearing homologous ACTH secreting pituitary tumors. This strain also has been established in the cheek pouch of non-conditioned hamsters but thus far has failed to grow in non-conditioned mice. 3. The use of quantitated tissue culture inocula for the production of tumors in the hamster cheek pouch for chemotherapeutic studies is suggested.
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