Abstract
Summary
1. Drinking habits of guinea pigs kept on a diet of dry food and drinking water have been studied to ascertain the amount of daily water consumption which may serve as a parameter for oral drug administration. 2. There is a difference between water intake of non-irradiated and irradiated animals. 3. This difference is chiefly accounted for by reduced water intake of animals succumbing to irradiation, which stopped drinking prior to death. 4. Water consumption of irradiated animals is not materially altered during the critical first 8 days after irradiation, irrespective of death rate produced later on. 5. Use of oral administration of water-soluble drugs with drinking water appears therefore possible with a sufficient degree of accuracy.
Get full access to this article
View all access options for this article.