Abstract
Summary
Individual anterior pituitaries as well as pooled glands of Macaca mulatta have been assayed in hypophysectomized immature female rats for their content of trophic hormones, particularly gonadiotrophic hormones. 1. In the adult female macaque, the content of follicle stimulating hormone was highest between the ninth and eleventh days of the cycle. The content of interstitial cell stimulating hormone was also maximum at this time of cycle. The ratio of ICSH to FSH was highest (10 to 1) on days 11 and 15. 2. In adult male anterior pituitary the total content of ICSH and FSH and the ratio between these hormones was approximately the same as in the adult female pituitaries at beginning and end of menstrual cycle. The gonadotrophic hormone content of pituitaries of immature animals was lower than in adults. 3. Other trophic hormones in the adult female pituitary, thyro trophic, adrenocortico-trophic and growth hormones, did not change in amount during the menstrual cycle. In adult male, as well as in the female pituitary, thyrotrophic and adrenocorticotrophic hormones were present in low concentration, but growth hormone was present in high unitage.
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