Abstract
Summary
1. The rate of penetration of crystallized C-RP into agar-antiserum medium has been determined. 2. With this procedure, the C-reactive protein present in human serum of 16 patients with rheumatic fever was evaluated. Variations of less than 0.001 mg of C-RP per ml of serum were detectable. 3. By observing the pattern of the precipitin bands at least 3 antigenic components were found to be present in crystalline C-reactive protein. 4. In human serum, the C-RP present appeared to contain up to 3 antigenic components in different concentrations.
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