Interrelationships of Methionine and Vitamin B 6 in Human Subjects. ∗

Abstract

Summary

1. A study of the interrelationship of methionine and pyridoxine was made in adult human subjects maintained on a semi-synthetic diet low in vit. B₆. 2. No effect of a high dosage of methionine on the urinary excretion of B₆ and its metabolites was observed in the study. 3. The role of vit. B₆ in the methylation of nicotinamide is shown by the increased urinary excretion of N¹-methylnicotinamide by human subjects, when given methionine plus pyridoxine but not when given only methionine.