Abstract
Summary
5-Hydroxytryptamine as well as histamine and heparin was demonstrated to be present in purified mast cells from the peritoneal washings of rats. The material was identified by bioassay and chromatography. The concentration of 5-hydroxytryptamine found in isolated mast cells agreed with that found by indirect means in the mast cells of the subcutaneous areolar tissue of rats. Implications of this finding are briefly discussed.
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