Abstract
Summary
Effects of reserpine, chlorpro-mazine and combined drugs on nest building and thermal preference of rats are described. In the doses used, reserpine alone had a marked and persistent effect on these functions. It depressed nest building while promoting choice of a warm environment. The differential behavioral effect is thought to be related to the great differences in persistence of activity required for the two tests and the ability of reserpine-treated animals to maintain alertness for brief periods after handling.
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