Relationship of Prolonged Drainage of Bile through Pancreatic Duct System to Pancreatitis. ∗

Abstract

Summary and Conclusions

1. The entire flow of bile was successfully diverted through the pancreatic duct system into the intestine in a total of 11 dogs. Eight of these dogs did not develop any significant degree of pancreatitis even though the average observation period for this group was more than 60 days, and only one dog in the series developed a full-blown acute pancreatic necrosis. 2. The results of these experiments indicate that the presence of bile in the pancreatic duct system under physiologic pressures is tolerated for long periods of time without any serious damage to the pancreas in most cases.